Overview: At St. Louis’ most lavish seafood restaurant, everything is posh and sleek, and the wine list shines. The oceans’ best appears with a minimum of fussiness—the emphasis is on the fish itself. 801 boasts the best chilled shrimp and fried clams this side of the Mississippi. Go early for the felicitous happy hour.
Dish: Work your way through a wide selection of oysters that are less than two days out of the sea.
Drink: The Old Fashioned, exquisitely and authentically concocted.
Tip: At $39, the three-course Sunday supper is a rare weekend dining bargain in Clayton.